2024 ICD-10-CM Diagnosis Code R77.1: Abnormality of globulin (2024)

Table of Contents
Abnormality of globulin Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedNoteThis chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.The conditions and signs or symptoms included in categories R00-R94 consist of:(a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;(b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;(c) provisional diagnosis in a patient who failed to return for further investigation or care;(d) cases referred elsewhere for investigation or treatment before the diagnosis was made;(e) cases in which a more precise diagnosis was not available for any other reason;(f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.Type 2 Excludesabnormal findings on antenatal screening of mother (O28.-)certain conditions originating in the perinatal period (P04-P96)signs and symptoms classified in the body system chapterssigns and symptoms of breast (N63, N64.5) Abnormal findings on examination of blood, without diagnosisType 2 Excludesabnormal findings on antenatal screening of mother (O28.-)abnormalities of lipids (E78.-)abnormalities of platelets and thrombocytes (D69.-)abnormalities of white blood cells classified elsewhere (D70-D72)coagulation hemorrhagic disorders (D65-D68)diagnostic abnormal findings classified elsewhere - see Alphabetical Indexhemorrhagic and hematological disorders of newborn (P50-P61) Other abnormalities of plasma proteins Other disorders involving the immune mechanism, not elsewhere classified FAQs
  1. ICD-10-CM Codes
  2. R00-R99
  3. R70-R79
  4. R77-
  5. 2024 ICD-10-CM Diagnosis Code R77.1

2024 ICD-10-CM Diagnosis Code R77.1: Abnormality of globulin (1)

Abnormality of globulin

    2016 2017 2018 2019 2020 2021 2022 2023 2024 Billable/Specific Code
  • R77.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursem*nt purposes.
  • The 2024 edition of ICD-10-CM R77.1 became effective on October 1, 2023.
  • This is the American ICD-10-CM version of R77.1 - other international versions of ICD-10 R77.1 may differ.

Applicable To

  • Hyperglobulinemia NOS

The following code(s) above R77.1 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations

that may be applicable to R77.1:

  • R00-R99

    2024 ICD-10-CM Range R00-R99

    Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

    Note

    • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
    • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
    • The conditions and signs or symptoms included in categories R00-R94 consist of:
    • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
    • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
    • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
    • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
    • (e) cases in which a more precise diagnosis was not available for any other reason;
    • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

    Type 2 Excludes

    • abnormal findings on antenatal screening of mother (O28.-)
    • certain conditions originating in the perinatal period (P04-P96)
    • signs and symptoms classified in the body system chapters
    • signs and symptoms of breast (N63, N64.5)

    Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
  • R70-R79

    2024 ICD-10-CM Range R70-R79

    Abnormal findings on examination of blood, without diagnosis

    Type 2 Excludes

    • abnormal findings on antenatal screening of mother (O28.-)
    • abnormalities of lipids (E78.-)
    • abnormalities of platelets and thrombocytes (D69.-)
    • abnormalities of white blood cells classified elsewhere (D70-D72)
    • coagulation hemorrhagic disorders (D65-D68)
    • diagnostic abnormal findings classified elsewhere - see Alphabetical Index
    • hemorrhagic and hematological disorders of newborn (P50-P61)

    Abnormal findings on examination of blood, without diagnosis
  • R77

    ICD-10-CM Diagnosis Code R77

    Other abnormalities of plasma proteins

      2016 2017 2018 2019 2020 2021 2022 2023 2024 Non-Billable/Non-Specific Code

    Type 1 Excludes

    • disorders of plasma-protein metabolism (E88.0-)
    Other abnormalities of plasma proteins

Clinical Information

  • Abnormally high globulin content of the blood.

ICD-10-CM R77.1 is grouped within Diagnostic Related Group(s) (MS-DRG v41.0):

  • 947 Signs and symptoms with mcc
  • 948 Signs and symptoms without mcc

Convert R77.1 to ICD-9-CM

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change

Code annotations containing back-references to R77.1:

  • Type 1 Excludes: D89

    ICD-10-CM Diagnosis Code D89

    Other disorders involving the immune mechanism, not elsewhere classified

      2016 2017 2018 2019 2020 2021 2022 2023 2024 Non-Billable/Non-Specific Code

    Type 1 Excludes

    • hyperglobulinemia NOS (R77.1)
    • monoclonal gammopathy (of undetermined significance) (D47.2)

    Type 2 Excludes

    • transplant failure and rejection (T86.-)

Diagnosis Index entries containing back-references to R77.1:

  • Abnormal, abnormality, abnormalities - see also Anomaly
    • globulin R77.1
  • Hyperglobulinemia R77.1

ICD-10-CM Codes Adjacent To R77.1

R75 Inconclusive laboratory evidence of human immunodeficiency virus [HIV]

R76 Other abnormal immunological findings in serum

R76.0 Raised antibody titer

R76.1 Nonspecific reaction to test for tuberculosis

R76.11 Nonspecific reaction to tuberculin skin test without active tuberculosis

R76.12 Nonspecific reaction to cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis

R76.8 Other specified abnormal immunological findings in serum

R76.9 Abnormal immunological finding in serum, unspecified

R77 Other abnormalities of plasma proteins

R77.0 Abnormality of albumin

R77.1 Abnormality of globulin

R77.2 Abnormality of alphafetoprotein

R77.8 Other specified abnormalities of plasma proteins

R77.9 Abnormality of plasma protein, unspecified

R78 Findings of drugs and other substances, not normally found in blood

R78.0 Finding of alcohol in blood

R78.1 Finding of opiate drug in blood

R78.2 Finding of cocaine in blood

R78.3 Finding of hallucinogen in blood

R78.4 Finding of other drugs of addictive potential in blood

R78.5 Finding of other psychotropic drug in blood

Reimbursem*nt claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2024 ICD-10-CM Diagnosis Code R77.1: Abnormality of globulin (2024)

FAQs

What is the ICD-10 code for globulin abnormalities? ›

ICD-10 code R77. 1 for Abnormality of globulin is a medical classification as listed by WHO under the range - Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified .

What is diagnosis code R77 1? ›

R77. 1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursem*nt purposes.

What does high level of globulin mean? ›

High globulin levels may be a sign of: Infection. Inflammatory disease. Immune disorders. Certain cancers, such as multiple myeloma, Hodgkin lymphoma (also called Hodgkin disease), or malignant lymphoma.

What is diagnosis code R77? ›

2024 ICD-10-CM Diagnosis Code R77: Other abnormalities of plasma proteins.

What is the disease associated with globulin? ›

A high globulin fraction may reflect increased globulin production and/or increased humoral immune activity, which can be seen in cases of leukemia, multiple myeloma, autoimmune liver diseases, as well as autoimmune and chronic inflammatory illnesses including IBD.

What is globulin disorder? ›

Inherited hemoglobin disorders fall into two main groups: the structural hemoglobin variants and the thalassemias, which are caused by defective globin production. They all follow a recessive form of inheritance. Those with a single defective globin gene—carriers or heterozygotes—are symptomless.

What level of globulin is alarming? ›

Results more than 3.5 g/dL for globulin and more than 2.5 for an albumin/globulin ratio are considered high. But being on bed rest for too long, dehydration, and problems during the blood draw can also cause a high reading. Your healthcare provider will likely order additional tests.

What organ does globulin affect? ›

Healthcare providers use globulin blood tests to measure protein levels in your blood. Your liver makes globulin, a protein. High levels may indicate autoimmune disease, infections or cancer. A low globulin reading may be a sign of liver or kidney disease.

What infection causes high globulin? ›

Raised levels of globulin proteins may indicate [1, 2]: Acute infection — such as pneumonia or hepatitis. Chronic inflammatory disease — such as rheumatoid arthritis or lupus. Dehydration — this may occur after a high fever or with diarrhoea and vomiting.

What is ICD code R77 2? ›

ICD-10 code: R77. 2 Abnormality of alphafetoprotein.

What is ICD R77 8? ›

8 Other specified abnormalities of plasma proteins.

What is the ICD-10 code for R87 1? ›

ICD-10 code: R87. 1 Abnormal findings in specimens from female genital organs Abnormal hormone levels.

What is the ICD-10 code for abnormal protein in blood? ›

ICD-10 code: R77. 9 Abnormality of plasma protein, unspecified.

What is the ICD-10 code for low gamma globulin levels? ›

2024 ICD-10-CM Diagnosis Code D80. 1: Nonfamilial hypogammaglobulinemia.

What is the ICD-10 code for D89 1? ›

ICD-10 code D89. 1 for Cryoglobulinemia is a medical classification as listed by WHO under the range - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism .

What is the ICD-10 code for abnormal IgE syndrome? ›

ICD-10-CM Code for Hyperimmunoglobulin E [IgE] syndrome D82. 4.

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